Bills vs. Lions odds, analysis, prediction.

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Bills @ Lions Betting Odds

Detroit Lions: -2.5 (-110)

Moneyline: -134

Buffalo Bills: +2.5 (-110)

Moneyline: +116

Over Under: 54.5 (-110)

Odds updated as of 12/14/24 courtesy of FanDuel


Overview:

Ford Field sets the stage for one of the NFL's most electrifying matchups of the season as the Detroit Lions (12-1) host the Buffalo Bills (10-3) in Week 15. This game features two powerhouse teams at the peak of their abilities, boasting the second-best combined record for an AFC vs. NFC clash this late in the season since 1970. With the Lions leading the league in offensive firepower and the Bills fueled by MVP front-runner Josh Allen, this battle is as much about playoff positioning as it is a potential preview of Super Bowl LIX. Both teams are loaded with talent, but each brings unique strengths and vulnerabilities, making this a must-watch contest with championship implications.

Here’s how each team can pave their way to victory, backed by detailed analysis and key statistics.

 

How the Lions can cover:

Dominate with a Balanced Offense

The Lions’ offense has been their backbone all season, leading the league in scoring (32.1 points per game) and ranking second in total offense (394.8 yards per game). They’ve found a rare balance between a potent passing attack and a bruising ground game, making them nearly impossible to defend.

Jared Goff has been a revelation, completing 72.4% of his passes for 3,265 yards and 25 touchdowns. His passer rating of 109.1 ranks second in the NFL, and his efficiency is unmatched in clean pockets, where he completes 79% of his passes for 9.1 yards per attempt. Goff’s ability to spread the ball around keeps defenses off-balance; his historic game against Green Bay last week, where six different players caught five or more passes, exemplifies Detroit’s offensive versatility.

On the ground, Jahmyr Gibbs and David Montgomery have formed one of the most dynamic duos in recent NFL history. Gibbs has rushed for 1,016 yards at 5.7 yards per carry (4th in the NFL) and has 30 runs of 10+ yards (2nd most). Montgomery complements him with power and red zone efficiency, scoring 12 rushing touchdowns (3rd in the league). Together, they’ve powered the Lions to 151.1 rushing yards per game (4th).

The Bills’ run defense has struggled, allowing 4.7 yards per carry (26th) and 49 runs of 10+ yards (26th). Detroit’s ability to control the ground game can set the tone early and keep Buffalo’s explosive offense sidelined.

Leverage an Elite Offensive Line

The Lions’ offensive line, ranked second by Pro Football Focus, is the backbone of their offensive dominance. Allowing a sack on just 5.98% of Jared Goff’s dropbacks and boasting a 13.7% stuffed rate (4th best), this unit excels in both pass protection and run blocking. With the return of left tackle Taylor Decker, the line is fully healthy and poised to deliver against Buffalo’s defense.

Right tackle Penei Sewell, one of the league’s best, will face Gregory Rousseau, Buffalo’s top pass rusher with 6.5 sacks. Sewell’s elite protection—allowing just a 6.6% pressure rate—ensures Goff can operate efficiently. Inside, Frank Ragnow, Graham Glasgow, and Jonah Jackson will take on Ed Oliver, whose quickness poses a challenge. Their ability to neutralize Oliver and maintain pocket integrity will be critical.

This line is also key to Detroit’s run game, which averages 151.1 rushing yards per game (4th). Against Buffalo’s 26th-ranked run defense, they can dominate the trenches, opening lanes for Jahmyr Gibbs and David Montgomery while controlling the game’s tempo. Their strength in short-yardage situations also fuels Detroit’s success in critical moments, including their 68.18% fourth-down conversion rate (6th).

By protecting Goff and creating opportunities on the ground, Detroit’s offensive line enables the Lions to dictate pace and exploit Buffalo’s defensive weaknesses. This unit is essential to their success in this high-stakes matchup.

Disrupt Josh Allen’s Rhythm

The Lions’ defense gets a significant boost this week with the return of Alim McNeill, DJ Reader, Levi Onwuzurike, and Josh Paschal. This bolstered defensive line will be tasked with pressuring Josh Allen, who has been sacked on just 3.17% of his dropbacks, the lowest rate in the NFL. Despite Allen’s ability to avoid sacks, consistent disruption can still throw him off rhythm.

Detroit leads the league in third-down blitz rate (45.4%), relying on aggression to force hurried decisions. While Allen thrives under pressure, boasting a 118.8 passer rating and 14 touchdowns against blitzes, relentless pressure could limit his deep shots and force him into shorter, less impactful plays.

The Lions’ secondary, anchored by Kerby Joseph (seven interceptions), will be critical in capitalizing on any mistakes. Allen’s propensity for big plays comes with some risks, and the Lions’ opportunistic defense will look to create turnovers from any errant throws under duress.

With fresh legs on the defensive line and an aggressive scheme, Detroit’s ability to consistently pressure Allen could disrupt Buffalo’s explosive offense and provide a decisive edge.

 

How the Bills can cover:

Let Josh Allen Take Over

Josh Allen remains Buffalo’s ultimate weapon and one of the league’s most dynamic players. Leading the NFL with 29 big-time throws and holding a 118.8 passer rating against the blitz (2nd best), Allen thrives under pressure, having thrown 14 touchdowns and just two interceptions in such situations. His ability to remain poised and deliver in challenging moments makes him uniquely equipped to handle Detroit’s aggressive blitz-heavy scheme.

Allen’s dual-threat capability adds another layer of difficulty for defenders. With six rushing touchdowns this season, he can extend plays and create opportunities on the ground, as seen in his historic game against the Rams, where he accounted for six total touchdowns.

The return of Dalton Kincaid (356 yards) and Keon Coleman (417 yards) bolsters Allen’s arsenal, adding to Khalil Shakir’s reliable presence (735 yards). These weapons, combined with Allen’s improvisational brilliance, make Buffalo’s offense incredibly difficult to contain. If Allen sustains his MVP-caliber play, he can carry the Bills to victory against even the most aggressive defenses.

Win the Turnover Battle

Buffalo excels in creating and protecting the football, leading the NFL in turnover margin (+1.3 per game) and averaging 1.8 takeaways per game (3rd). The defense, anchored by Christian Benford and Tyler Rapp, thrives in opportunistic playmaking. Benford has allowed a minuscule passer rating of 6.0 when targeted and defended eight passes, while Rapp has contributed two interceptions, further solidifying Buffalo’s ability to capitalize on opponents’ mistakes.

On the offensive side, Josh Allen is careful with the football, throwing interceptions on just 1.26% of his attempts (7th). This ball security will be critical against a Detroit defense that ranks 6th in takeaways (1.5 per game), led by playmakers like Kerby Joseph (seven interceptions). By avoiding turnovers and generating extra possessions, Buffalo can maintain control of the game and tilt the balance in their favor.

Capitalize in Situational Football

Buffalo’s ability to thrive in high-leverage situations gives them a significant edge. Defensively, they rank 5th in opponent red zone touchdown percentage (47.2%) and 2nd in opponent fourth-down conversions (35%). These strengths allow them to neutralize opposing offenses in critical moments, a necessary strategy against Detroit’s high-powered attack, which ranks 6th in both red zone efficiency (67.3%) and fourth-down conversions (68.18%).

On offense, Buffalo excels at keeping drives alive and finishing in scoring positions. They lead the league in fourth-down conversion percentage (86.67%) and rank 8th in third-down conversion rate (43.42%). These numbers reflect their ability to sustain momentum and capitalize on opportunities, forcing opponents to adjust and play catch-up.

By dominating situational football on both sides of the ball, the Bills can control the flow of the game, limit Detroit’s offensive opportunities, and create the scenarios necessary to emerge victorious.

Pressure Jared Goff

Buffalo’s pass rush, led by Gregory Rousseau (6.5 sacks), Von Miller (4 sacks), and A.J. Epenesa (5 sacks), will be key to disrupting Detroit’s offense. Rousseau’s ability to generate pressure off the edge will challenge Penei Sewell, while Von Miller’s big-game experience and Ed Oliver’s interior quickness can collapse the pocket. Forcing Jared Goff out of his comfort zone is critical, as his effectiveness drops significantly under pressure compared to his elite performance in clean pockets (79% completion, 9.1 yards per attempt).

Buffalo’s selective use of stunts, twists, and well-timed blitzes can create mismatches against Detroit’s otherwise dominant offensive line. Complementing this with tight coverage from Christian Benford and Taron Johnson will force Goff to hold the ball longer, increasing the chances of sacks or hurried throws.

To sustain pressure throughout the game, Buffalo must rotate players like DaQuan Jones and Jordan Phillips to stay fresh against Detroit’s physical line. Maintaining discipline to contain Goff’s subtle pocket movements will further limit his ability to extend plays. Consistent disruption will be key to neutralizing Detroit’s explosive offense and creating opportunities for Buffalo’s defense to capitalize.

Algorithm’s Projection:

Detroit Lions 29 Buffalo Bills 27

The algorithm predicts a razor-thin victory for the Detroit Lions, edging out the Buffalo Bills 29-27 in what promises to be a thrilling, high-stakes matchup. The Lions’ balanced offensive attack, led by Jared Goff and their dominant offensive line, is expected to set the tone, while their opportunistic defense capitalizes on timely pressures to keep Josh Allen in check. However, the Bills won’t make it easy, as Allen’s MVP-caliber play and Buffalo’s knack for excelling in situational football will keep them within striking distance. In the end, Detroit’s efficiency in the red zone and ability to control the tempo could make the difference in this potential Super Bowl preview.


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